Intrinsic chief executive Richard Freeman is to depart the network in early 2017.
Freeman has been chief executive since 2010, having first joined as sales director.
Freeman will be replaced by Intrinsic managing director Andy Thompson, but will retain a role within Old Mutual following the transition.
In a statement, Freeman says: “We have the right successor in Andy Thompson and I will remain in the Old Mutual Wealth business to allow for a smooth transition.
“I have worked with Andy for nearly 15 years; his strategic knowledge and understanding of what it takes to deliver for clients will ensure Intrinsic goes from strength to strength. I look forward to leading Intrinsic through 2016, which will be a pivotal year for the business.”